Renal cell cancers
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Author: Diana Roberts
Renal cell cancer is one of the few tumors in which well-documented cases of spontaneous tumor regression in the absence of therapy exist, but this occurs very rarely and may not lead to long-term survival. Surgical resection is the mainstay of treatment of this disease. Renal cell cancer (also called kidney cancer or renal cell carcinoma) is a disease in which malignant (cancer) cells are found in the lining of tubules (very small tubes) in the kidney. There are two kidneys, one on each side of the backbone, above the waist. Renal cell cancers have historically been resistant to treatment with chemotherapy; only 10?15% of patients experience an anticancer response to currently available single chemotherapy drugs.
Renal cell cancers arising from the kidney epithelium account for 90-95% of all primary renal cell cancers and clear cell is the most common histology (75%). Renal cell cancer also may spread to the lungs, bones, or liver. And it may spread from one kidney to the other. Renal cell cancer, also called renal adenocarcinoma, or hypernephroma, can often be cured if it is diagnosed and treated when still localized to the kidney and to the immediately surrounding tissue. The probability of cure is directly related to the stage or degree of tumor dissemination.
Renal cell cancer (also called kidney cancer or renal cell adenocarcinoma) is a disease in which malignant cancer cells form in tubules of the kidney. Approximately 54,000 Americans are diagnosed with kidney cancer each year, according to the National Cancer Institute. Renal cell cancer comes in a number of forms, with the most common being renal cell carcinomas, which account for the majority of cases of kidney cancer . When a patient is diagnosed with kidney cancer, a pathologist will examine a sample of tissue from the kidneys to determine which type of renal cell cancer is involved, as the treatment recommendations will vary depending on which form of cancer is responsible.
Renal cell carcinoma develops within the kidney tissue. Rarely, both kidneys can be affected at the same time. Renal cell carcinoma (RCC, aka hypernephroma) is the most common form of kidney cancer arising from the proximal renal tubule. It is the most common type of kidney cancer in adults. Renal cell carcinoma (RCC) is a rare malignancy, but one in which significant progress in treatment options has occurred during the past several years. Approximately 35% of patients with RCC present with stage IV disease, and 20% to 40% of patients who undergo surgical resection will ultimately develop metastatic disease.
Renal cell cancer, the commonest form of kidney cancer, affecting around 200,000 people worldwide each year, is currently difficult to manage in its advanced or metastatic stage (mRCC). Around a third of patients already have metastases when their cancer is diagnosed and their prospects of surviving more than a year or two have been bleak. Renal cell cancer (also called kidneycancer or renal adenocarcinoma) is a disease in which malignant (cancer) cells are found in the lining of tubules (very small tubes) in the kidney. There are 2 kidneys, one on each side of the backbone, above the waist. Renal cell carcinoma accounts for approximately 85% of all kidney tumors. These tumors occur twice as often in men as in women and usually occur in adults between the ages of 50 and 70.
Renal cell cancer is the most common type of kidney cancer, and accounts for about 85 percent of all kidney tumors. It is more common in men than women, usually occurring in men over 55 years old. Renal cell carcinoma typically occurs in people over the age of 50 and is twice as likely to occur in men than in women. Renal cortical tumors account for nearly 90 percent of all kidney tumors. Other tumors of the kidney, namely transitional cell tumors, can form in the kidneys as well as the ureters.
Symptoms caused by these processes include pain (in the flank, abdomen or back) and blood in the urine (small amounts may not be visible). If cancer spreads beyond the kidney, symptoms depend upon which organ is involved. Symptoms may appear as the tumor grows.
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